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Systems Biology Applied to Immune Safety
Welcome!
We are delighted that you have chosen the Immuno-Safety Tools module to start or enhance your current educational journey in immuno-safety science. This lecture is one in a series of seven providing detailed information on tools currently used to evaluate and characterize the status of the immune system in a preclinical setting. Please review the learning objectives below for more information on what you will learn in this lecture.
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Target Audience
This course is intended for the science professional or graduate student looking to learn the fundamental science and key considerations that are examined in immune safety assessment. The advanced topics offered in this module are intended to take a deeper dive into specific scientific areas. These courses are recommended for the more experienced scientist with a firm grasp of the information highlighted in the introduction module.
Learning Objectives
The learner will be able to:
- Compare and contrast relevant attributes of at least three assay platforms for systems-level study of immune safety.
- Give an example of a functional immune readout and how it provides information that a phenotypic assay may not provide.
- Describe three relevant classes of high-dimensional data analysis algorithms, with at least one example of each.
- Discuss the difficulties involved with defining the range of “normal” for parameters in the immune system, and how these can be overcome.
Additional Information
| Attachment | Size |
|---|---|
 Systems Biology Applied to Immune Safety slide deck - Maecker | 7.22 MB |
Lectures in this module
Clinical pathology in preclinical immuno-safety assessment
Immunopathology: Evaluation from Discovery to Safety Assessment
TDAR assessments
Cytokine Release Syndrome (CRS)
Immunophenotyping
Systems biology applied to immune safety
Immunogenicity characterization tools (ADAs, complement, immune complexes)
Holden T. Maecker, PhD
Professor (Research), Microbiology & Immunology
Director, Human Immune Monitoring Center
Stanford University School of Medicine
Professor (Research), Microbiology & Immunology
Director, Human Immune Monitoring Center
Stanford University School of Medicine
Available Credit
- 0.50 Participation
Price
Cost:
$25.00
Required Hardware/software
This platform, Ethos CE, works with most modern web browsers (e.g., Chrome, Internet Explorer, MS Edge, Safari). Contact itc@hesiglobal.org if you are having any difficulties with this platform.