We are delighted that you have chosen the Immuno-Safety Tools module to start or enhance your current educational journey in immuno-safety science. This lecture is one in a series of seven providing detailed information on tools currently used to evaluate and characterize the status of the immune system in a preclinical setting. Please review the learning objectives below for more information on what you will learn in this lecture.
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This course is intended for the science professional or graduate student looking to learn the fundamental science and key considerations that are examined in immune safety assessment. The advanced topics offered in this module are intended to take a deeper dive into specific scientific areas. These courses are recommended for the more experienced scientist with a firm grasp of the information highlighted in the introduction module.
The learner will have an:
- understanding what immunophenotyping is and what it can be used for.
- understanding of basic flow Cytometry, the technology used for IP (and what quality parameters/pitfalls to look for).
- understanding of basic IP markers in different tissues and species, how these compare to humans.
- an understood basic interpretation of IP data (as well as challenges, pitfalls and potential follow ups).
- an idea on additional more specific readouts that can be added to the basic parameters to answer additional questions.
Lectures in this module
Clinical pathology in preclinical immuno-safety assessment
Immunopathology: Evaluation from Discovery to Safety Assessment
Cytokine Release Syndrome (CRS)
Systems biology applied to immune safety
Immunogenicity characterization tools (ADAs, complement, immune complexes)
Birgit Fogal, Ph.D.
- 0.50 Participation