Safety Considerations for Oligonucleotides

Welcome!

We are delighted that you have chosen the Therapeutic Modalities module to start or enhance your current educational journey in immuno-safety science. This lecture is one in a series of five providing detailed information on current and/or emerging therapeutics that interact with the immune system and is led by Dr. Padmakumar Narayanan at WAVE Life Sciences. Please review the learning objectives below for more information on what you will learn in this lecture.
 
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Target Audience

This course is intended for the science professional or graduate student looking to learn the fundamental science and key consideration that are examined in immune safety assessment. Advanced topics and coursed that take a deeper dive into specific scientific areas will be offered and are recommended for the more experienced scientist who has a firm grasp of the information highlighted in the introduction module.

Learning Objectives

 
The learner will be able to:
 
  • Explain the key designs/features and mechanisms that oligonucleotide-based therapies use to modulate targets inaccessible to small and large molecule therapeutics. 
  • Explain and analyze impact of specific oligonucleotide chemistry and design on immunomodulatory/pro-inflammatory potential of oligonucleotides.
  • Evaluate the regulatory perspectives involved in oligonucleotide development for, widely prevalent to rare to ultrarare, genetic diseases.

Additional Information

Course summary
Available credit: 
  • 1.00 Participation
Course opens: 
03/22/2022
Course expires: 
03/30/2027
Cost:
$35.00
Rating: 
0

Lectures in this module

 
CAR Therapy
 
Safety Considerations for Oligonucleotides
 
CD3-binding (T cell engaging) immune stimulating antibody-based therapies
 
Gene Therapy
 
Nonclinical Development of Biologics
Padmakumar Narayanan, DVM, MS, PhD
WAVE Life Sciences

Available Credit

  • 1.00 Participation

Price

Cost:
$35.00
Please login or register to take this course.

Required Hardware/software

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